http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478519-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42
filingDate 2016-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106478519-B
titleOfInvention A kind of preparation method of 2- methyl -4- amino -6- chlorine pyrimidine
abstract The invention discloses a kind of preparation methods of 2- methyl -4- amino -6- chlorine pyrimidine to obtain purpose product 2- methyl -4- amino -6- chlorine pyrimidine by two-step reaction with 4,6- dihydroxy -2- methylpyrimidine, phosphorus oxychloride, aminating agent etc. for raw material.Operation of the present invention is easy, and comprehensive yield is 81% or more, and more existing 68% or so yield has and is obviously improved, significantly reduces existing drug production cost, is suitble to industrial-scale production.
priorityDate 2016-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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