http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106475569-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B22F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
| filingDate | 2015-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106475569-B |
| titleOfInvention | A kind of preparation method of metal nanometer cluster, nanocluster obtained by this method and the contrast agent comprising the nanocluster |
| abstract | The present invention provides a kind of preparation methods of metal nanometer cluster, including, a mixed liquor is provided, the mixed liquor includes metal salt, template or the template comprising disease target ligand；Make the mixture system that redox reaction occur, the metal ion that the metal salt is included is reduced to metallic atom, the metallic atom forms the metal nanometer cluster by acting on the template；Wherein, the template is selected from albumen, peptide, polymer or DNA.Metal nanometer cluster of the invention, have many advantages, such as PET imaging: radio-labeled stability greatly improves, it is ensured that the accuracy of diagnosis；The some superior characteristics of nanocluster are given in the extra small partial size of nanocluster and the cause of water-soluble peptide shell；The presence of template avoids the use of the big loop coupling agent for coupling radiometal ion, and template can be used to coupling function molecule, such as small peptide, the small molecule etc. of some diseases targeting. |
| priorityDate | 2015-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.