http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106474569-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-145
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14
filingDate 2016-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106474569-B
titleOfInvention A kind of preparation method of the critical hydrogel of carboxymethyl chitin
abstract The present invention provides a kind of completely new gel form --- preparation methods of critical gel, use carboxymethyl chitin for raw material, Nantural non-toxic amino acid --- lysine is as modifier, catalytic action through coupling reagent 4- (4,6- dimethoxy-triazine -2- base) -4- methyl morpholine hydrochloride (DMTMM) is prepared.The main feature of this gel is that viscous modulus and elasticity modulus are equal always, that is, possesses two kinds of speciality of high viscosity and high resiliency.Terminal sterilization can be achieved in " critical state " of modified gel, extends the internal residence time, realizes single dose injection;Nontoxic amino acid modification object remains the intrinsic biocompatibility of carboxymethyl chitin and bioactivity, will not bring any security risk;Viscous modulus and elasticity modulus increase simultaneously and remain equal, improve the viscoelastic property of carboxymethyl chitin, while keeping the original liquid condition of itself, are easy to inject reduction pain.
priorityDate 2016-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.