http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106474468-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32434 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 |
| filingDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106474468-B |
| titleOfInvention | Compound adjuvant, vaccine containing compound adjuvant and preparation method of vaccine |
| abstract | The invention relates to a composite adjuvant, a vaccine containing the composite adjuvant and a preparation method of the vaccine, wherein the composite adjuvant comprises a noncompetitive inhibitor of indoleamine-2,3 dioxygenase and an aluminum salt, the noncompetitive inhibitor of indoleamine-2,3 dioxygenase is 4-phenylimidazole, and the content of the 4-phenylimidazole is 0.5-1.5 mg; the aluminum salt is aluminum hydroxide, and the content of the aluminum hydroxide is 300 mu g. The composite adjuvant has the advantages of easily available raw materials, simple preparation process, low cost, stable performance and small toxic and side effects, promotes immune response from positive and negative aspects of body immune regulation, is safe and reliable to use within an immune dose range, can effectively induce antigen-specific humoral immune response, remarkably enhances antigen-specific humoral immune response, and has an effect superior to that of a vaccine without adjuvant, a single adjuvant and an aluminum adjuvant group. |
| priorityDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.