| abstract |
The present invention relates to a probe of formula (I), and a physiologically acceptable salt, solvate or hydrate thereof; Wherein: X 1 =NH, O or S; X 2 =O or S; SE is an unstable group which can be removed under the action of stimuli, especially the presence of enzymes, chemical compounds or probes containing The physicochemical characteristics of the medium; A is an aromatic group, which releases a chromophore or a fluorophore after C(X 2 )‑O bond cleavage in aqueous solution; R is a hydrogen atom or ‑(L)n‑GP, where n is equal to 0 or 1, L is a connecting arm, and GP is a water-soluble group. The subject of the invention is also its synthetic intermediates and detection methods using them. |