http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106467517-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 2016-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106467517-B |
| titleOfInvention | Deuterium-modified Abemaciclib derivatives |
| abstract | The invention belongs to the field of medicinal chemistry, and in particular relates to deuterium-modified Abemaciclib derivatives, a preparation method thereof, a pharmaceutical composition containing deuterium-modified Abemaciclib derivatives, deuterium-modified Abemaciclib derivatives and pharmaceutical compositions thereof for the preparation and treatment of cell proliferation diseases Uses in medicine. Compared with Abemaciclib, some compounds of the present invention (especially the compounds of the Examples) have better pharmacokinetic properties, which is expected to reduce the clinical dosage, thereby reducing treatment costs and benefiting more patients. |
| priorityDate | 2015-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.