http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106459083-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5386 |
| filingDate | 2015-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106459083-B |
| titleOfInvention | Amide derivatives of 1-oxa-4,9-diazaspiroundecane compounds with multimodal antipain activity |
| abstract | The present invention relates to compounds having dual pharmacological activity against sigma (σ) receptors and μ-opioid receptors, and more particularly, to diazaspiroundecane compounds having such pharmacological activity, which Processes for the preparation of class compounds, pharmaceutical compositions comprising them, and their use in therapy, in particular, in the treatment of pain. (for formula 1) where Y is (formula 2) or (formula 3) n is 1 or 2; q is 1, 2, 3, 4, 5 or 6; X is a bond, -C(O )O‑, ‑C(O)NR 8 ‑, ‑C(O)‑, ‑O‑ or ‑C(R 4 R 4 )‑; R 1 is C(O)R 5 or S(O) 2R5 . |
| priorityDate | 2014-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.