http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106432422-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate | 2016-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106432422-B |
| titleOfInvention | One group of peptide and its pharmaceutical composition and application with analgesic activity |
| abstract | The invention discloses one group peptide and its pharmaceutical composition and application with analgesic activity has such as the amino acid sequence as shown in sequence table SEQ ID No.1 or sequence table SEQ ID No.2 or, their pharmaceutically acceptable salt.On the basis of it is existing for the head end and terminal cysteine, the amino acid sequence as shown in sequence table SEQ ID No.1 or SEQ ID No.2, one or more amino acid are deleted, after displacement or addition the still polypeptide with analgesic activity or, their pharmaceutically acceptable salt.Then the present invention filters out the polypeptide with analgesic activity to the polypeptide to polypeptide is formed after deletion, displacement or the addition of amino acid one or more in the Loop 3 of GsMTx-4.By polypeptide to the testing result of rat nociceptive pain model, inventor confirms to have obtained the short chain series of the polypeptide with analgesic activity, completes the present invention. |
| priorityDate | 2016-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.