http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106432182-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7645b337960b4895ea9079b72f1215c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-02 |
| filingDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_610ef116c9626a1e324440cf24e6ab85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56c7b543c266eab828086e76a50e293d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f32683449db0063b19293a6be84271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e813169e41c251e3702c1d8a28de4b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abca9c5d679104da75ce02d2a94ca2bd |
| publicationDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106432182-A |
| titleOfInvention | The synthetic method of tedizolid intermediate |
| abstract | The invention provides a method for synthesizing a tedizolid intermediate. The synthetic method of tedizolid intermediate comprises the following steps: step A: make the cyano group in compound (I) and alcohol generation addition reaction, generate the acid salt of compound (II) or compound (II); Step B: use Hydrazine group or methylhydrazine group replace the alkoxyl group on the acid salt of described compound (II) or compound (II), generate compound (III); Step C: make compound (III) and sodium nitrite under acidic condition The following reaction generates tedizolid intermediate (IV). The overall reaction is The invention solves the problems of explosive and highly toxic reaction reagents, difficulty in separating by-products of methyl isomerism, and the like. |
| priorityDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.