| abstract |
The invention provides a decellularized cartilage scaffold, which mainly comprises components of a cartilage decellularized scaffold of silk fibroin, snail mucin, sterol, toad or frog, the mechanical strength and the degradation speed of the cartilage scaffold can be controlled by changing the component proportion, the decellularized cartilage scaffold is in a three-dimensional solid shape, has good mechanical properties, is provided with fine and dense cavities on the surface, and is beneficial to the adhesion and regeneration of cartilage cells. The decellularized cartilage scaffold is prepared without heating and using any chemical or enzyme crosslinking agent, and the activity of each component is preserved. The decellularized cartilage scaffold exerts the synergistic advantages of various components and is applied to replacement grafts of cartilage tissues. |