http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106414717-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-515 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0635 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate | 2015-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106414717-B |
titleOfInvention | cells that produce human antibodies |
abstract | The object of the present invention is to provide avian B cells expressing various human antibodies. The present invention takes, as a solution, avian B cells in which all or a part of DNA sequences derived from a human antibody light chain variable region and a human antibody light chain constant region are inserted into the antibody light chain locus , or replace all or part of the DNA sequences derived from the variable region of the light chain of a human antibody and the constant region of the light chain of a human antibody, and in the locus of the heavy chain of the antibody, insert the variable region of the variable region of the heavy chain of a human antibody and the variable region of a human antibody All or part of the DNA sequence of the heavy chain constant region, or replaced with all or part of the DNA sequence derived from the variable region of the heavy chain of a human antibody and the constant region of the heavy chain of a human antibody, and in the antibody light chain pseudogene locus, the insertion Two or more DNA sequences derived from the variable region of the light chain of a human antibody, or replaced with two or more DNA sequences derived from the variable region of the light chain of a human antibody, and/or two or more inserted into the pseudogene locus of the heavy chain of the antibody The above DNA sequences derived from human antibody heavy chain variable regions may be substituted with two or more DNA sequences derived from human antibody heavy chain variable regions. |
priorityDate | 2014-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 143.