| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7e87f29e0db9416800cab4f60f6c468 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
| filingDate |
2015-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36d9d687af5aa808e7ac7fdefebee6f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1eeeef58f83035ffe3ae186e2bdbc16c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8b364faa051d4bde4d4eef1018214f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_994bfeab51dba6ee9c1b7c6b89a975d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0ca8628f6045f4edb3d7c57f037d7dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fbc9e7e640e2d2f1545409aeb194842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a8074e094b5ef20c1320a359e552342 |
| publicationDate |
2017-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-106414438-A |
| titleOfInvention |
2-amidothiazole derivatives or salts thereof |
| abstract |
Provided are compounds useful as active ingredients of pharmaceutical compositions for treating urinary storage disorders, voiding disorders, and lower urinary tract diseases. The present inventors have found that thiazole derivatives substituted at the 2-position of pyrazine carbonylamino are excellent positive allosteric modulators of muscarinic M3 receptors, and expect them to act as muscarinic M3 receptor - mediated bladder contractions. Related prophylactic or therapeutic agents for bladder/urological diseases, thus completing the present invention. The 2-acylaminothiazole derivatives or salts thereof of the present invention are expected to be used as prophylactic or therapeutic agents for bladder/urological diseases (such as voiding disorders such as hypoactive bladder) associated with muscarinic M receptor-mediated bladder contraction . |
| priorityDate |
2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |