http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106407665-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-30
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
filingDate 2016-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106407665-B
titleOfInvention A kind of people's transthyretin chaff interferent virtual screening method
abstract The invention discloses a kind of virtual screening methods of people's transthyretin chaff interferent, belong to Assays for Screening Environmental Endocrine Disruptors method field.Its virtual screening process is to be primarily based on ten groups chemicals is classified, then it uses quantitative structure activity relationship model prediction per class chemicals to the disturbing effect of people's transthyretin, and then judges whether chemicals there is interference people's transthyretin to transport the ability of thyroxine and the power of interference performance according to the effect value of prediction.The concise flow for screening people's transthyretin chaff interferent that the present invention announces is reasonable, and method is accurate and reliable, is easily achieved sequencing, is applicable to the virtual screening of potential people's transthyretin chaff interferent and potential interference object priority level initializing in application domain.
priorityDate 2016-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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