http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106399349-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-76 |
filingDate | 2016-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106399349-B |
titleOfInvention | Aburamycin A, A3 biosynthesis and purifying technique |
abstract | The invention discloses a kind of aburamycin A, A3 biosynthesis and extraction and purification process, comprise the steps:1) SrcmRI Gene overexpression engineering bacteria SR1 structure;2) SrcmRII Gene knockout engineering bacteria SR2 structure;3) SrcmRI Gene overexpression and SrcmRII Gene knockout engineering bacteria SR3 structure;4)By step 1)‑3)Fermentation and product extraction in the engineering bacteria liquid medium within of structure obtain chromomycin extract solution;5)By step 1)‑3)Culture and product extraction of the engineering bacteria of structure on solid medium obtain chromomycin extract solution;6)By step 4)Or step 5)In chromomycin extract solution purified and analyzed acquisition final product aburamycin A and chromomycin A3.The present invention is formed by the structure of genetic engineering bacterium;Yield is high, and accessory substance is few, and purification of products technique is simple;Operating process is easy to control, pollution-free, and production cost is low. |
priorityDate | 2016-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.