http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106397527-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0033 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 2016-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106397527-B |
| titleOfInvention | Mifepristone derivatives and application thereof |
| abstract | The invention discloses a kind of Mifepristone derivatives and application thereof.Shown in the structural formula of the Mifepristone derivatives such as formula (I)；Wherein R is acyl group or sulfonyl；The invention further relates to purposes of the Mifepristone derivatives in tumour medicine of the preparation treatment with KLF5 regulation, the especially purposes in treatment triple negative breast cancer drug.The compound structure is simple, easily prepared；Anti-tumor activity is strong compared with mifepristone, and dosage is small, it can be used for treating the preparation of triple negative breast cancer and the tumour medicine closely related with KLF5, simultaneously, one kind that the present invention explores synthesis has the Mifepristone derivatives of high druggability, also provides new resolving ideas and scheme for the synthesis of other similar compounds. |
| priorityDate | 2016-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.