http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106390195-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 |
filingDate | 2016-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106390195-B |
titleOfInvention | A kind of method of modifying of collagem membrane |
abstract | The invention discloses a kind of method of modifying of collagem membrane: using culture plate as template, collagen, freeze overnight is added;For 24 hours by gained sample vacuum freeze drying, collagem membrane is prepared;Epigallo-catechin gallate (EGCG) is subjected to solution preparation;The collagem membrane of preparation is placed in precrosslink in EGCG, is soaked in the 0.05mol/L acetum containing EGCG, for 24 hours in 4 DEG C of crosslinkings, lXPBS buffer rinses 3 times;The composite membrane prepared is immersed in 1% PEG20000, soaked overnight, then flushed three times with PBS buffer solution, lyophilized overnight.The beneficial effects of the present invention are: provide a kind of collagen composite membrane for possessing more preferable mechanical performance, anti-inflammatory and biocompatibility, improve the mechanical performance of former collagem membrane, reduce drug-collagen composite membrane bio-toxicity, it has a good application prospect, provides new selection for the operation of the related bones increment such as guided bone regeneration. |
priorityDate | 2016-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.