http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106390127-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
filingDate | 2015-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106390127-B |
titleOfInvention | A kind of New Liver Kupffer's cells swallows composite restrainer and its application of Nano medication particle |
abstract | The present invention relates to a kind of new liver withered Fou Shi (Kuppfer) cell phagocytosis Nano medication particle inhibitor combination and its in the application of Nano medication, while including a effective amount of inflammatory cytokine inhibitor and phagocytosis approach restrainer: the phagocytosis approach restrainer is one of following inhibitor or a variety of: giant cell drinks inhibitor, pinocytosis, clathrin dependence endocytosis inhibitor, small recessed protein dependent endocytosis and the phagocytosis approach restrainer for relying on actin;The inflammatory cytokine inhibitor is one of following inhibitor or a variety of: NF-kB signal path specific inhibitor and other inflammatory factor inhibitor.It is expected to realize that reduce Nano medication is swallowed by liver KC, extends its circulation time in vivo, drug effect is better achieved, reduce toxic side effect, there is potential applicability in clinical practice. |
priorityDate | 2015-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.