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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-55
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-8984
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-8984
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
filingDate 2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106389879-B
titleOfInvention Application of dendrobium nobile lindl total alkaloids
abstract The invention discloses an application of dendrobium nobile lindl total alkaloids in preparing a medicine for preventing or treating acute and chronic liver injury diseases. Dendrobium total alkaloid pair CCL 4 Alcohol or D-galactose induced acute liver injury, CCL 4 The chronic liver injury caused by the liver disease has prevention and treatment effects. After the dendrobium nobile lindl total alkaloids are used, ALT and AST activities in serum can be obviously reduced, MDA content of liver homogenate is obviously reduced, and Nrf2, Nqo1 and Ho-1mRNA expression are improved. By observation of liver tissue slices, after the dendrobium nobile lindl total alkaloids are used, the lesion necrosis of the liver tissue disappears, the structure of liver lobule is basically complete, and inflammatory cell infiltration is obviously reduced.
priorityDate 2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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