http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106389321-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d366ba9e14f490e6c63aa4cbd4ae056 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
filingDate | 2016-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56f09518f55b15692dabb69ed10ee197 |
publicationDate | 2017-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106389321-A |
titleOfInvention | Pharmaceutical composition capable of improving stability of Shenmai drug injection |
abstract | The invention discloses a pharmaceutical composition capable of improving the stability of a Shenmai drug injection. The pharmaceutical composition for injection is mainly prepared through the steps that salt of Shenmai is dissolved into water for injection, and oxalic acid and/or sodium oxalate is added to regulate the pH value of drug liquid by serving as a pH regulator, wherein the dosage of oxalic acid and/or sodium oxalate is 1 mg/100 ml-100.0 mg/100 ml. According to the pharmaceutical composition, the pH value of the injection is made to be more stable, and Shenmai degradation substances are greatly reduced compared with the prior art; on the condition that usage of other cosolvent capable of increasing clinical application risks is avoided, the clarity of the Shenmai injection is improved, and the problem that the Shenmai injection generates small white dots, white blocks and solution turbidity on the condition that the Shenmai injection is preserved for a long time by adopting a product in the prior art is particularly solved; it can be guaranteed that inspection of visible foreign matter of the product meets the regulations of a drug quality standard, and clinical medication and popularization are convenient. |
priorityDate | 2016-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.