| abstract |
The invention discloses a 2'-dialkyl-substituted nucleoside analogue and its use. The 2'-dialkyl-substituted nucleoside analogue is a nucleoside represented by general formula I, a nucleoside phosphoramidate compound, or a pharmaceutically acceptable prodrug, salt, solvate, stereoisomer, tautomer or polymorphic form, metabolite thereof. The preparation is convenient and the performance is excellent. |