http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106349718-A

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00
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filingDate 2016-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4be95e069121e65825ab06f0acc93358
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_065c4ef6111b87615b06ab8e09d477e3
publicationDate 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106349718-A
titleOfInvention A kind of preparation method of antibacterial collagen
abstract The invention relates to a preparation method of antibacterial collagen, which comprises the following steps: (1) dissolving the collagen in a buffer solution, controlling the mass concentration of the collagen to be 0.1% to 15%, to obtain a collagen solution; (2) adding to the step ( 1) Add modified triclosan to the collagen solution in , heat up to 25-50° C., react for 0.1-48 hours to obtain an antibacterial collagen solution; (3) prepare the antibacterial collagen solution obtained in step (2) at 0-4 ℃ dialysis for 0.5 ~ 96h, and then freeze-dried to obtain antibacterial collagen. In the antibacterial collagen prepared by the present invention, the antibacterial components are firmly combined in the collagen with covalent bonds, and the antibacterial effect is more durable. For example, it can be prepared into antibacterial collagen gel, collagen sponge, wound dressing, and cell scaffold for tissue engineering. And other biomedical materials, the material has antibacterial effect throughout the life cycle.
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priorityDate 2016-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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