| abstract |
The invention discloses a triazole derivative with HSP90 inhibitory activity, its preparation method and application. Specifically, the present invention relates to a triazole derivative having a structure of formula (I), its stereoisomer or a pharmaceutically acceptable salt thereof, wherein the definition of each substituent in formula (I) is the same as that in the description. These compounds with novel structures have heat shock protein HSP90 inhibitory activity, can be used for treating cancer, neurodegenerative diseases, inflammatory diseases, autoimmune diseases, ischemic brain injury and the like, and have broad application prospects. |