http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106349151-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106349151-B |
| titleOfInvention | The impurity G and its method of purification and purposes generated by methylphenidate hydrochloride preparation process |
| abstract | The present invention provides a kind of impurity G generated by methylphenidate hydrochloride preparation process and its method of purification and purposes, method of purification to include the following steps：1) crude product of impurity G is added in into the first solvent, dissolved by heating, be filtered to remove insoluble matter, slow cooling crystallization, solid is dried, obtains filter cake by filtering；2) filter cake obtained by step 1) is added in into the second solvent, dissolved by heating, slow cooling crystallization, then insulated and stirred while crystallization filters, solid is dried, obtains the fine work of the impurity G.Impurity G is synthesized by the intermediate steps in the preparation process of methylphenidate hydrochloride in the present invention, and separating-purifying is carried out to reaction filtrate and obtains impurity G, the purity ＞ 99% of impurity G, impurity carries out qualitatively and quantitatively in being produced to methylphenidate hydrochloride, for analyzing the purity and content of detection methylphenidate hydrochloride, available for the quality of control methylphenidate hydrochloride raw material and its preparation, the safe medication for broad masses provides safeguard. |
| priorityDate | 2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.