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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-08
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filingDate 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106349104-B
titleOfInvention Oxime and oximido ether compound with anti-hepatitis B activity
abstract The invention discloses oxime and oximido ether compound with anti-hepatitis B activity, structure is below general formulaļ¼š It is confirmed by HepG 2.2.15 cell experiments, oxime of the invention and oximido ether compound all have certain inhibitory action to HBV surface antigen (HBsAg) and e antigens (HBeAg).Under the same terms, positive controls Lamivudine only has HBsAg inhibiting rates 55.51%, and the oxime and oximido ether compound of the present invention can reach HBsAg inhibiting rates 98.67%, and has the characteristics that toxicity is low.The novel oxime and oximido ether compound of the present invention is Nonnucleoside anti-hepatitis B activity compound, is expected to be developed further into the new drug for anti-hepatitis virus.
priorityDate 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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