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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203
filingDate 2016-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106336442-B
titleOfInvention Gastrodin derivative, preparation method, its application and pharmaceutical preparation
abstract This application provides a kind of gastrodin derivative and preparation method thereof, containing substituted naphthalene nucleus in the gastrodin derivative;Present invention also provides the preparation methods of gastrodin derivative.The application uses turbidimetry for Determination platelet aggregation rate, to evaluate the gastrodin derivative to the inhibiting rate of platelet aggregation, the experimental results showed that, gastrodin derivative provided by the present application has apparent blood coagulation resisting function, it can be used as potential lead compound, the application in the drug of preparation treatment thrombus, cardiovascular and cerebrovascular disease, apoplexy and other diseases relevant to blood coagulation.
priorityDate 2016-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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