http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106319001-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate | 2016-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106319001-B |
| titleOfInvention | Industrialized preparation method and application of recombinant interferon gamma |
| abstract | The invention provides an industrialized production method for expressing, renaturing and purifying an inclusion body of recombinant interferon gamma (rpIFN gamma) by escherichia coli. In particular to: 1. constructing an rpIFN gamma escherichia coli expression strain; 2. developing a rpIFN gamma high-density fermentation process; 3. the denaturation and renaturation process development of rpIFN gamma inclusion bodies; 4. and (3) purifying and preparing the rpIFN gamma sample after renaturation. Through the technical clearance of the 4 layers, the rpIFN gamma produced by the method has higher biological activity (the specific activity reaches 5-7 multiplied by 10) 7 U/mg), and the method has high yield (up to more than 1.5 g/L), low cost and easy amplification. |
| priorityDate | 2016-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.