http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106318916-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10022 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
| filingDate | 2016-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106318916-B |
| titleOfInvention | Recombined adhenovirus and tetravalence adenovirus vaccine and preparation method thereof |
| abstract | The invention discloses a kind of recombined adhenovirus and tetravalence adenovirus vaccine and preparation method thereof, the tetravalence recombinant adenovirus vaccine, including 3 type adenopathy strains of recombination, 55 type adenopathy strains of 7 type adenopathy strains of recombination, 14 type adenopathy strains of recombination and recombination.The present invention passes through preparation first and includes the recombinant shuttle plasmid including different hexon gene segments, endotoxin test method is carried out with recombination human 3-type adenoviral gene group, the recombined adhenovirus genome that hexon gene segment is replaced by 7 types, 14 types, 55 types is obtained, rescue obtains the different recombination human 3-type of major capsid protein-hexon, 7 types, 14 types, 55 type recombined adhenovirus after transfecting cell.It mixes by same protein content, then is inactivated with interior third rouge of β-after purification, obtain tetravalence adenovirus vaccine, which can induce the Neutralizing antibody response to four kinds of serotype adenovirus, and neutralization titer is 500-1000. |
| priorityDate | 2016-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.