| abstract |
The invention relates to a 2-substituted-benzimidazole-4-formamide compound, a preparation method, and an application thereof. The structure of the 2-substituted-benzimidazole-4-formamide compound is represented as the general formula (I), wherein R1, R2, Y1, Y2, R3 and X are defined as the claims and the specifications. The invention also discloses a medicine composition comprising the 2-substituted-benzimidazole-4-formamide compound or pharmaceutically acceptable salts thereof. The 2-substituted-benzimidazole-4-formamide compound and the medicine composition can be used for preparing medicines for treating diseases related to Poly ADP-ribose polymerase, e.g., malignant tumor. |