http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106310383-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L89-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 |
filingDate | 2016-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106310383-B |
titleOfInvention | Injectable bone repair hydrogel and preparation method thereof |
abstract | The invention discloses an injectable bone repair hydrogel and a preparation method thereof, wherein the hydrogel is prepared by immobilizing poly-dopamine (PDA) -modified calcium-phosphorus particles on degradable natural macromolecules with aldehyde groups, and mixing the degradable natural macromolecules with amino groups with the aldehyde groups immobilized with the PDA-modified calcium-phosphorus particles for Schiff base reaction. The hydrogel is formed by reacting natural polymers through Schiff base under physiological conditions, and a crosslinking agent or an initiator with biological/cell toxicity is not required to be added. The reaction condition is mild, no violent heat release exists, the peripheral tissue damage is not caused in clinical application, and the method is suitable for clinical bone repair materials. |
priorityDate | 2016-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.