http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106290680-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106290680-B |
| titleOfInvention | The analysis method of the intermediate S- cyanogen methyl isothiourea of cefmetazole acid |
| abstract | The present invention relates to a kind of Content and related substances determination methods of intermediate S- cyanogen methyl isothiourea for synthesizing cefmetazole acid, in particular to a kind of starting material thiocarbamide and impurity 2 for detecting S- cyanogen methyl isothiourea simultaneously, synthesizing the intermediate, the method for 4- Diaminothiazoles.This method is measured using high performance liquid chromatography, and chromatographic column is using octyl bonded silica gel as filler, and using the p- organic phase of buffer salt-ion as mobile phase, the acid solution or buffer using mobile phase or pH less than 3 are as diluent.Under this methodology, thiocarbamide, S- cyanogen methyl isothiourea and 2,4- Diaminothiazoles obtain good separation, and S- cyanogen methyl isothiourea also obtains good separate with impurity. |
| priorityDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.