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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02
filingDate 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106290643-B
titleOfInvention A kind of method of quality control of Chinese medicine schizonepeta anti-lung cancer activity ingredient
abstract The invention belongs to the field of Chinese medicines more particularly to a kind of method of quality control of Chinese medicine schizonepeta anti-lung cancer activity ingredient.The preparation of specific step is as follows (1) test solution;(2) using the apoptosis necrosis rate of lung cell A549 as evaluation index, pharmacy in vitro evaluation is carried out to the schizonepeta alcohol extract of 9 batches of separate sources;(3) high performance liquid chromatograph is used, the mode of gradient elution establishes schizonepeta alcohol extract HPLC finger-print;(4) Characteristic chromatographic peak is extracted;(5) pharmacodynamics index and chromatographic peak peak area are subjected to grey correlation correlation analysis;(6) preparation of reference substance solution;(7) the biggish chromatographic peak of the degree of association that (5) step is obtained ingredient is carried out to point out;(8) to the assay of anti-lung cancer activity ingredient in the Chinese medicine schizonepeta alcohol extract pointed out.The present invention have method simplicity, objectivity, globality by force etc. advantages, the method for foundation can accurately reflect the active constituent and total quality feature of schizonepeta alcohol extract.
priorityDate 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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