http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106290635-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2016-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106290635-B |
titleOfInvention | A kind of drug screening method that the anti-melanin based on Beads enrichment generates |
abstract | The drug screening method that the anti-melanin based on Beads enrichment that the invention discloses a kind of generates, this method acquires (LC-MS) technology using Magnetic Isolation and chemical information, target proteins conjugate is analyzed, the screening and evaluation of drug anti-melanin nucleus formation are used for.The pH value, ionic strength and denaturation cleaning solution of solution when the present invention filters out best incubation temperature, incubation time, incubation by many experiments.The present invention is compared with conventional screening methods, it is remarkably improved screening efficiency, shortens screening time, and it can be found that the synergistic effect between compound, it can be used in the screening of extensive natural products library or combinatorial chemical library, it is suitable for carrying out the discovery of the screening and lead compound that generate anti-melanin drug (including chemical synthetic drug and natural products) in early stage, there are quick, accurate, high repeatability and other advantages. |
priorityDate | 2016-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.