http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106279303-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106279303-B |
| titleOfInvention | N-4- benzene sulfonamido-N ' -1- deoxidations-(2- deoxidation -2- substituted-aminos)-β-D- glucopyranosyl thiourea compounds and application thereof |
| abstract | Have the invention discloses one kind and inhibits carbonic anhydrase Activity so reach anti-tumor metastasis invasion effect have general formula（ ）Shown structure it is novel N 4 benzene sulfonamidos N The deoxidation of ' 1 (2 deoxidation, 2 substituted-amino) β D glucopyranosyl thiourea compounds.Such compound in structure have sulfanilamide (SN), three active fragments of substituted-amino glucose and thiocarbamide, by with carbonic anhydrase In Zn 2+ Ion forms coordinate bond, realizes the catalytic activity for inhibiting enzyme, plays the effect of anti-tumor metastasis invasion, has potential application in terms of as antitumor drug.General formula of the present invention（ ）In R be defined in the specification. |
| priorityDate | 2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.