http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106279277-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106279277-B |
| titleOfInvention | A kind of fluorescence probe for detecting S-nitrosation and its preparation and application |
| abstract | The present invention provides a kind of fluorescence probe for detecting S-nitrosation, and 3 hydroxyphthalimides substituted by N R bases occur condensation reaction with 2 diphenylphosphine yl benzoic acids in anhydrous methylene chloride and are made.Fluorescence probe stability provided by the invention is good, can preserve use for a long time；With larger absorption launch wavelength it is poor (>100nm), the interference of exciting light can effectively be avoided；Due to probe in physiological environment unstressed configuration itself, only just have fluorescence after being reacted with SNO, product of the generation with hyperfluorescence, therefore, detection signal-to-noise ratio is high, and sensitivity is good；With outstanding selectivity, protein s nitrosylation can be specifically detected in complex biological sample；With good biological membrane permeability, so as to realize the specific detection to S-nitrosation modification.The general structure of probe of the present invention is as follows： |
| priorityDate | 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.