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filingDate 2016-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106267198-B
titleOfInvention It targets photo-thermal therapy combined immunization and treats antitumor compound formulation and the preparation method and application thereof
abstract Combined immunization is treated the present invention relates to a kind of targeting photo-thermal and treats antitumor compound formulation and the preparation method and application thereof, is made of Cypate liposome, adriamycin-bovine serum albumin(BSA) (ADM-BSA) and hyaluronic acid-adriamycin (HA-ADM).Cypate is substantially better than free Cypate by chemical stability after liposome entrapment, and external temperature rise effect is stronger, has good tumor-targeting and photo-thermal therapy effect.The targeting of Cypate liposome is good, with stronger photo-thermal therapy effect, dual-target hyaluronic acid-haptens immune formulation of immunization therapy and active targeting chemotherapy is constituted in conjunction with ADM-BSA and HA-ADM, remaining for deep and transfer tumour cell therapeutic effect is good, it can achieve the purpose that synergistic treatment to avoid the defect in respective treatment.
priorityDate 2016-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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