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filingDate 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106265701-B
titleOfInvention A kind of temperature sensitive hydrogel eye drops and its preparation method and application
abstract The invention discloses a kind of temperature sensitive hydrogel eye drops and its preparation method and application, the eye drops contains prescription active constituent, gel-type vehicle, preservative, metal ion chelation agent, isotonic regulator and water for injection, the prescription active constituent includes neomycinsulphate and dexamethasone sodium phosphate, the gel-type vehicle includes poloxamer188 and PLURONICS F87, and the preservative includes benzalkonium bromide;The metal ion chelation agent is disodium ethylene diamine tetraacetate;The isotonic regulator is sodium chloride.As a preference of the present invention, the eye drops further includes moisturizer and bioadhesive material.Eye drops disclosed by the invention has several advantages that (1) convenient drug administration, and medical fluid has adherency, delay and slow releasing function on eye mask surface, the compliance that can be reduced administration frequency, reduce drug wastage, increase patient;(2) preparation process is simple, at low cost, is suitble to large-scale production;(3) antibacterial and anti-inflammatory effects are good, and irritation is small, highly-safe.
priorityDate 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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