| abstract |
The present invention discloses a kind of Enrofloxacin nanosuspension and preparation method thereof, it is prepared by Enrofloxacin and stabilizer to Enrofloxacin nanosuspension, and the mass ratio of the Enrofloxacin and stabilizer is 1:(0.1~10)；The stabilizer is one or more of Tween 80, soybean lecithin, PVP K30, PLURONICS F87, poloxamer188, hydroxypropyl methyl cellulose, NaTDC, sodium starch glycolate, glycerin monostearate, polyethylene glycol 400, Labraso, Gelucire 44/14, Miglyol 812.The present invention also provides a kind of preparation methods.Enrofloxacin nanosuspension of the invention, the Enrofloxacin nanosuspension drug concentration height, good absorbing, long action time, stability are good, moreover it is possible to improve its bioavilability. |