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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91dd090bcd6317461f595ff8e639faad
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
filingDate 2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e1390bac7047aea26c5bfcc388d2fd8
publicationDate 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106257285-A
titleOfInvention Positive relationship between AQP1 and β-catenin and pathologic grading of cancer
abstract The present invention relates to biomedicine field, the forward particularly related between AQP1 and β-catenin and pathologic grading of cancer contacts.The present invention explores the propagation of the glioblastoma cells caused by AQP1 expression in specific cells model and clinical sample and AQP1 overexpression and aggressivity raises, and patients with gliomas Overall survival (OS) and Progression free survival phase (PFS) lower and the action mode of β-catenin up-regulated in patients with gliomas body.And find that AQP1 and β-catenin expression is closely related with pathologic grading of cancer, histological grade, Overall survival (OS) and Progression free survival phase (PFS) many factors by the Cox Return Law, further demonstrate that the forward between AQP1 and β-catenin and pathologic grading of cancer contacts.
priorityDate 2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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