http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106243107-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 |
| filingDate | 2016-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106243107-B |
| titleOfInvention | A kind of N2, the preparation method of 9 diacetyl guanines |
| abstract | The invention belongs to technical field of chemistry, more particularly to a kind of N 2 , the preparation method of 9 diacetyl guanines.Its step is：Guanine is dissolved in pyridine under agitation, then 4 dimethylamino naphthyridine DMAP catalyst are added in guanine pyridine solution A, 5 ± 1 DEG C is cooled to, acylating agent chloroacetic chloride is slowly added dropwise, process control temp is added dropwise and is less than 10 DEG C；After being added dropwise, 2 4h are reacted at room temperature, obtain reaction solution containing X1；B, X1 reaction solutions are heated, be evaporated under reduced pressure, removed material X2 and X3, separate out the solid containing X1；C, the solid containing X1 obtained by distillation water wash step B, is filtered to remove X4 and X5；D, by the solid containing X1 obtained by step C by stirring and dissolving in acetum, be filtered to remove insoluble matter X6, obtain the filtrate containing X1；The invention enables N 2 , for 9 diacetyl guanine total recoverys up to 90.2%, the purity of product reaches 99.5%. |
| priorityDate | 2016-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.