http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106236719-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-714 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-714 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2016-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106236719-B |
| titleOfInvention | Pharmaceutical composition containing mecobalamin and preparation method thereof |
| abstract | The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a pharmaceutical composition containing mecobalamin and a preparation method thereof. The pharmaceutical composition containing mecobalamin comprises the following components in percentage by mass: 0.01-1% of mecobalamin, 1-10% of stabilizing agent, 40-95% of diluent, 0-20% of disintegrating agent and 0.1-10% of lubricant; the preparation method comprises the steps of premixing mecobalamin and part of diluent, mixing the premix with the stabilizer, the diluent and the disintegrant to obtain mixed powder, mixing the mixed powder with the lubricant for a certain time to obtain mixed raw and auxiliary material powder, and directly tabletting and coating the mixed raw and auxiliary material powder. The dry granulation is adopted, the process steps are few, the influence of moisture and heat on the main drug is avoided, the quality of the mecobalamin tablets is further improved, the cost is reduced, and the industrial production is facilitated. |
| priorityDate | 2016-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.