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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65
filingDate 2016-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106226285-B
titleOfInvention A kind of Jin Weihe dopamine is " Raman quiet zone " substrate and its preparation method and application of shell
abstract The invention belongs to separation of biopolymer analysis technical fields, specially using Jin Weihe dopamine as " Raman quiet zone " substrate of shell and its preparation method and application.Preparation process of the present invention includes: to be reduced directly gold nanoparticle with hydro-thermal method, borax soln is dissolved in after centrifugation again, " Raman quiet zone " molecule (E) -2- ((4- (acetenyl) benzal) amino) ethanethio of hydro-thermal method preparation is added;Then micro silver nitrate is added, then dopamine is added, makes its in-situ reducing Nano silver grain;By the auto polymerization of dopamine, the Raman substrate of stable " Raman quiet zone " is generated.Experiment shows that the novel Raman microprobe molecule realizes the Raman image effect excellent to cell interior in increasing under surface enhanced acts on for gold nanoparticle, and base material of the invention is without template, low cost, hypotoxicity are applied to living cells imaging, it is easy to operate, it is novel convenient, it is practical and efficient.
priorityDate 2016-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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