http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106222243-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate | 2016-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106222243-B |
titleOfInvention | A circRNA marker, kit and gene chip for the diagnosis of schizophrenia |
abstract | The invention belongs to the field of biotechnology, and relates to a circRNA marker and a kit for schizophrenia diagnosis and efficacy evaluation. The present invention provides a circRNA marker for schizophrenia diagnosis, including hsa_circRNA_101835, hsa_circRNA_101836, hsa_circRNA_102101, hsa_circRNA_102315, hsa_circRNA_103102, hsa_circRNA_103704 and hsa_circRNA_104597, and the primer sequences of the above seven circRNAs are as shown in SEQ ID NO. 14; probes for the above seven circRNAs are also provided, and the probe sequences are shown in SEQ ID NO.15 to SEQ ID NO.21. The present invention also provides a circRNA marker for evaluating the efficacy of anti-schizophrenia drugs. The beneficial effect of the present invention is to provide schizophrenia biomarkers and circRNA biomarkers for evaluating the efficacy of antipsychotic drugs for the first time. After clinical verification, it has high specificity and sensitivity value, and has a high diagnostic reference value. As a schizophrenia-specific biomarker, circRNA will bring revolutionary changes in the diagnosis and treatment of schizophrenia. |
priorityDate | 2016-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.