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filingDate 2016-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106214671-B
titleOfInvention a preparation containing tramadol hydrochloride and acetaminophen, and its preparation method
abstract The invention provides a preparation containing tramadol hydrochloride and acetaminophen and a preparation method thereof, wherein the preparation comprises the following components in parts by weight: 45 parts of tramadol hydrochloride, 390 parts of acetaminophen, 10-15 parts of lactose, 303.2-4 parts of povidone K and 3-4.2 parts of magnesium stearate. The preparation method of the preparation is realized by the steps of crushing and sieving, weighing and proportioning, granulating, total mixing, intermediate inspection, filling and polishing or tabletting, aluminum-plastic packaging and the like. The preparation provided by the invention is simple in prescription and small in auxiliary material dosage, long-term tests and accelerated tests prove that the content of related substances in the preparation is small, the contents of acetaminophen and tramadol hydrochloride are basically unchanged, and no acetaminophen is detected.
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