http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106188297-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2016-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106188297-B |
| titleOfInvention | Nano antibody Nb91 of anti-CTLA-4 and the preparation method and application thereof |
| abstract | The invention discloses nano antibody Nb91 of anti-CTLA-4 and the preparation method and application thereof.Nano antibody provided by the present invention includes determinant complementary region and framework region；The determinant complementary region of the nano antibody is made of CDR1, CDR2 and CDR3；The amino acid sequence of the CDR1 is the 26-32 amino acids of SEQ ID No.7 in sequence table；The amino acid sequence of the CDR2 is the 48-55 amino acids of SEQ ID No.7 in sequence table；The amino acid sequence of the CDR3 is the 94-106 amino acids of SEQ ID No.7 in sequence table.Nano antibody Nb91 of the invention can be applied to the research and development of CTLA-4 Molecular Detection reagent in conjunction with T cell and CTLA-4, prepare tumor inhibitor or inhibiting tumour cells agent and preparation inhibits CTLA-4 activity and promotes the drug of T cell proliferation. |
| priorityDate | 2015-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.