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filingDate 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106188229-B
titleOfInvention It is a kind of using free glycine and L-cysteine as the synthetic peptide of pharmacological activity group
abstract The invention belongs to biomedicine technical fields, and in particular to a kind of synthetic peptide and its purposes in preparation treatment cerebral injury drug.The amino acid sequence of the synthetic peptide is X1- (Gly-L-Cys) n-L-Ala-X2-X3(I), in formula, X1 be without or L-Phe, X2 be without L-Cys, X3 be without or L-Phe, X1, X3 cannot simultaneously be nothing, n≤8.Animal experiments show that such synthetic peptide can pass through intravenous administration approach under extremely low dosage; through blood-brain barrier; reach brain; hydrolysis generates free glycine and cysteine and plays neuroprotection under the action of intracerebral proteolytic enzyme; the ischemic perfusion injury for reducing brain plays the purpose for the treatment of cerebral apoplexy.
priorityDate 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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