http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106187984-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-51 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-86 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 2016-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106187984-B |
titleOfInvention | A kind of mouth xanthones compounds and its preparation method and application |
abstract | The invention discloses a kind of mouth xanthones compounds for suppressing 5 alpha-reductases(1), the mouth xanthones compounds are from black purple Swertia patens( Swertia atroviolacea )In it is isolated, its molecular formula is C 18 H 18 O 5 , the Compound nomenclature is:The methyl mouth mountain ketone of 6 (2 ethoxy) 1,7 dimethoxy 3, the entitled methyl xanthone of 6 (2 hydroxyethyl) 1,7 dimethoxy 3 of English, has following structural formula: (1)The preparation method of the mouth xanthones compounds, be using black purple Swertia patens as raw material, extracted through medicinal extract, MCI decolourings, silica gel column chromatography, high pressure liquid chromatography separating step and obtain.The mouth xanthones compounds have good inhibiting effect through 5 alpha-reductase active testings to 5 alpha-reductases.The compounds of this invention is simple in construction, and has preferable 5 alpha-reductase inhibitory action, can be as the lead compound for preparing 5 alpha reductase inhibitors. |
priorityDate | 2016-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.