http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106187800-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 |
filingDate | 2016-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106187800-B |
titleOfInvention | A kind of class EDTA ligands containing adjacent two phenolic hydroxyl groups and non-gadolinium magnetic resonance contrast agent and preparation method thereof |
abstract | The invention discloses a kind of class EDTA ligands 2 containing adjacent two phenolic hydroxyl groups, 2 '; 2 "; 2 " ' ((3 (3,4 dihydroxy phenyls) 1,2 diyl of propane) ethylenediamine tetraacetic acid (EDTA), non-gadolinium paramagnetic metal complex magnetic resonance contrast agent and Fei Ga metal clusters collective magnetic resonance contrast agent based on the ligand and preparation method thereof.The present invention has prepared 2 first, 2 '; 2 "; 2 " ' ((3 (3,4 dihydroxy phenyls) propane 1,2 diyls) ethylenediamine tetraacetic acid (EDTA), the advantages of the ligand binding adjacent two kinds of structures of two phenolic hydroxyl groups and EDTA, non-gadolinium magnetic resonance contrast agent based on the ligand is respectively provided with higher relaxivity, preferable water-soluble and structural stability;Compared with the Gd class contrast agent of Clinical practice, using the orderly metal cluster collective contrast agent of Coordinate self-assembly, MRI imaging effects more preferably, can show more details, provided for a variety of medicals diagnosis on disease and more accurately analyze foundation. |
priorityDate | 2016-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.