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filingDate 2016-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106178106-B
titleOfInvention The method that 3D printing sodium alginate/polyvinyl alcohol is physical crosslinking double-network hydrogel bracket entirely
abstract The invention discloses a kind of methods that 3D printing sodium alginate/polyvinyl alcohol is physical crosslinking double-network hydrogel bracket entirely.Technical solution includes that the colloidal sol with thixotropic property is made after fumed silica mixing is added in the mixed solution containing SA/PVA, and 3D printing is carried out in this, as printed material and obtains colloidal sol bracket, then colloidal sol bracket is first freezed make polymer P VA cause polymerization and full cross-linked Cheng Yichong network obtain preforming gel stent, thaw at RT is then taken out, then preforming gel stent is immersed in CaCl 2 In aqueous solution, keeps SA full cross-linked into another heavy gel network, obtain hydrogel scaffold.The method that present invention process is simple, production procedure is short, control is easy, production cost is low, the 3D printing of good reliability sodium alginate/polyvinyl alcohol is physical crosslinking double-network hydrogel bracket entirely, obtained hydrogel scaffold is nontoxic, good mechanical performance, water absorption rate are high and good biocompatibility.
priorityDate 2016-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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