| abstract |
The present invention relates to compounds of formula (I), wherein Y is C-R 1' ; R 1' is hydrogen or halogen; R 1 is hydrogen or halogen; R 2 is hydrogen, lower alkyl or phenyl; R 4 is hydrogen or lower alkyl ; or R and R may together with the corresponding atoms to which they are attached form the following rings: ( A ), (B), (C), (D) or (E) ; R is hydrogen or lower alkane and if R2 and R4 form a ring as described above, then R5 is hydrogen ; or R4 and R5 may together with the C atom to which they are attached form a heterocycloalkyl ring; R3 is phenyl or Pyridyl, wherein the N atom in the pyridyl group may be in a different position; or relates to a pharmaceutically acceptable salt or acid addition salt, racemic mixture, or corresponding enantiomer and/or optical isomer thereof and/or stereoisomers. The compounds can be used to treat Parkinson's disease, anxiety, vomiting, obsessive-compulsive disorder, autism, neuroprotection, cancer, depression and type 2 diabetes. |