abstract |
Provided herein are methods for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering senolytic agents. Aging-related diseases and conditions treatable by the methods of using senolytic agents described herein include cardiovascular diseases and conditions associated with or caused by: arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis chronic obstructive pulmonary disease; osteoarthritis; aging-related eye diseases and conditions; and aging-related skin diseases and conditions. |